About P-POD
This tool, developed by the Genome Databases Group at Princeton, displays families of predicted orthologs from P. falciparum, H. sapiens, D. melanogaster, M. musculus, A. thaliana, C. elegans, D. rerio, and S. cerevisiae with an emphasis on providing information about disease-related genes and experimental confirmation of orthology from the literature. Families of related sequences are generated using two different methods: OrthoMCL and Jaccard Clustering. Disease-related information and literature is collected from the OMIM database, the Saccharomcyes Genome Database (SGD). For more information, see the Help page.
All the data, database schema, and software are available for download here. For more information, please refer to the paper describing P-POD.
Search:
Option 1: Enter a gene/protein name or identifier, choose the organism of the query protein, and select the type of analysis:
Search tips:-
Choose the OrthoMCL option to view families that consist only of putative orthologs (and also in-paralogs when appropriate, see the Help page for details); choose Jaccard Clustering to view larger families of related proteins.
- Valid search entries for each organism are listed
in the table below:
Organism Source Database Valid gene/protein identifier(s) Examples P.falciparum PlasmoDB PlasmoDB ID PF08_0034 H.sapiens ENSEMBL ENSEMBL peptide ID, peptide name ENSP00000266970, CDK2 D.melanogaster FlyBase FlyBase ID CG17520-PA, CkIIalpha-PA M.musculus ENSEMBL ENSEMBL peptide ID ENSMUSP00000068896 A.thaliana TAIR TAIR identifier or gene name AT1G25490.1, PAB4 C.elegans WormBase WormBase identifier or gene name C09G4.1, dbr-1 D.rerio ENSEMBL ENSEMBL peptide ID, ZFIN ID ENSDARP00000007117, ZDB-GENE-040808-60 S.cerevisiae SGD ORF name or gene name YNL098C, DPM1